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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD2
All Species:
8.48
Human Site:
T24
Identified Species:
15.56
UniProt:
Q96C19
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C19
NP_077305.2
240
26697
T24
E
G
E
G
G
G
E
T
P
E
Q
P
G
L
N
Chimpanzee
Pan troglodytes
XP_001156210
410
44344
T194
E
G
E
G
G
G
E
T
P
E
Q
P
G
L
N
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
Dog
Lupus familis
XP_848956
248
27200
P24
R
G
Q
R
E
T
R
P
V
L
P
A
R
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y0
240
26773
T24
E
G
E
G
G
E
A
T
E
Q
P
G
L
N
G
Rat
Rattus norvegicus
Q4FZY0
239
26741
T24
E
D
E
G
G
E
A
T
E
Q
P
G
L
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
Chicken
Gallus gallus
P09860
161
18412
Frog
Xenopus laevis
NP_001089944
202
23367
V25
E
D
H
G
G
D
A
V
P
E
Q
P
R
R
R
Zebra Danio
Brachydanio rerio
NP_001038676
233
26492
A24
E
D
G
S
H
E
P
A
A
A
L
D
E
A
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
N24
D
S
P
S
S
T
T
N
T
D
S
S
E
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
D24
N
E
G
D
E
Q
G
D
S
R
R
V
Q
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
25.8
62
N.A.
94.1
93.3
N.A.
60
20
70.4
75
N.A.
45.8
N.A.
N.A.
53.3
Protein Similarity:
100
58.2
37.9
68.9
N.A.
97
96.6
N.A.
64.1
38.7
76.6
83.7
N.A.
60.8
N.A.
N.A.
63.7
P-Site Identity:
100
100
0
6.6
N.A.
40
33.3
N.A.
0
0
46.6
6.6
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
0
13.3
N.A.
46.6
40
N.A.
0
0
46.6
13.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
24
8
8
8
0
8
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
24
0
8
0
8
0
8
0
8
0
8
0
0
0
% D
% Glu:
47
8
31
0
16
24
16
0
16
24
0
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
0
31
16
39
39
16
8
0
0
0
0
16
16
0
16
% G
% His:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
8
0
16
24
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
0
0
0
0
16
16
% N
% Pro:
0
0
8
0
0
0
8
8
24
0
24
24
0
0
8
% P
% Gln:
0
0
8
0
0
8
0
0
0
16
24
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
8
0
0
8
8
0
16
8
8
% R
% Ser:
0
8
0
16
8
0
0
0
8
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
16
8
31
8
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _